Previous studies have demonstrated the ability of reprogramming endochondral bone into induced pluripotent stem (iPS) cells, but whether similar phenomenon occurs Kitchen in intramembranous bone remains to be determined.Here we adopted fluorescence-activated cell sorting-based strategy to isolate homogenous population of intramembranous calvarial o
The potential contribution of the natural products from Brazilian biodiversity to bioeconomy
ABSTRACT The development of our Gift Card society has been based on the use of biodiversity, especially for medicines and nutrition.Brazil is the nation with the largest biodiversity in the world accounting for more than 15% of all living species.The devastation of biodiversity in Brazil is critical and may not only cause the loss of species and ge
Pediatric Brain Stem Death Perspectives for the Future in India
Pediatric brain stem death needs to be recognized both for futility in resuscitative efforts and in scope for organ donation.Pediatric donation can be performed from 37 weeks gestational age to 18 years.The diagnosis of brain stem death is completed by two clinical examinations separated by an interval of 24 h in term newborns and neonates and 12-h
ER stress affects processing of MHC class I-associated peptides
Abstract Background Viral infection and neoplastic transformation trigger endoplasmic reticulum (ER) stress.Thus, a large proportion of the cells that must be recognized by the immune system are stressed cells.Cells respond to ER stress by launching the unfolded protein response (UPR).The UPR regulates the two key processes that control major histo