Pediatric Brain Stem Death Perspectives for the Future in India

Pediatric brain stem death needs to be recognized both for futility in resuscitative efforts and in scope for organ donation.Pediatric donation can be performed from 37 weeks gestational age to 18 years.The diagnosis of brain stem death is completed by two clinical examinations separated by an interval of 24 h in term newborns and neonates and 12-h

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ER stress affects processing of MHC class I-associated peptides

Abstract Background Viral infection and neoplastic transformation trigger endoplasmic reticulum (ER) stress.Thus, a large proportion of the cells that must be recognized by the immune system are stressed cells.Cells respond to ER stress by launching the unfolded protein response (UPR).The UPR regulates the two key processes that control major histo

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